RIG-I, a novel DAMPs sensor for myoglobin activates NF-κB/caspase-3 signaling in CS-AKI model

BACKGROUND: Acute kidney injury (AKI) is the main life-threatening complication of crush syndrome (CS), and myoglobin is accepted as the main pathogenic factor. The pattern recognition receptor retinoicacid-inducible gene I (RIG-I) has been reported to exert anti-viral effects function in the innate...

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Detalles Bibliográficos
Autores principales: Wang, Peng-Tao, Li, Ning, Wang, Xin-Yue, Chen, Jia-Le, Geng, Chen-Hao, Liu, Zi-Quan, Fan, Hao-Jun, Lv, Qi, Hou, Shi-Ke, Gong, Yan-Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8215750/
https://www.ncbi.nlm.nih.gov/pubmed/34148549
http://dx.doi.org/10.1186/s40779-021-00333-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8215750/
https://www.ncbi.nlm.nih.gov/pubmed/34148549
http://dx.doi.org/10.1186/s40779-021-00333-4

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