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RIG-I, a novel DAMPs sensor for myoglobin activates NF-κB/caspase-3 signaling in CS-AKI model

BACKGROUND: Acute kidney injury (AKI) is the main life-threatening complication of crush syndrome (CS), and myoglobin is accepted as the main pathogenic factor. The pattern recognition receptor retinoicacid-inducible gene I (RIG-I) has been reported to exert anti-viral effects function in the innate...

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Detalles Bibliográficos
Autores principales:	Wang, Peng-Tao, Li, Ning, Wang, Xin-Yue, Chen, Jia-Le, Geng, Chen-Hao, Liu, Zi-Quan, Fan, Hao-Jun, Lv, Qi, Hou, Shi-Ke, Gong, Yan-Hua
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8215750/ https://www.ncbi.nlm.nih.gov/pubmed/34148549 http://dx.doi.org/10.1186/s40779-021-00333-4

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