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Depletion of EREG enhances the osteo/dentinogenic differentiation ability of dental pulp stem cells via the p38 MAPK and Erk pathways in an inflammatory microenvironment

BACKGROUND: Epiregulin (EREG) is an important component of EGF and was demonstrated to promote the osteo/dentinogenic differentiation of stem cells from dental apical papilla (SCAPs). Whether EREG can stimulate the osteo/dentinogenic differentiation of dental pulp stem cells (DPSCs) in inflammatory...

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Detalles Bibliográficos
Autores principales: Ran, Ran, Yang, Haoqing, Cao, Yangyang, Yan, Wanhao, Jin, Luyuan, Zheng, Ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8215766/
https://www.ncbi.nlm.nih.gov/pubmed/34154572
http://dx.doi.org/10.1186/s12903-021-01675-0