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Differential seeding and propagating efficiency of α-synuclein strains generated in different conditions

BACKGROUND: Accumulation of alpha-synuclein (α-syn) is a main pathological hallmark of Parkinson’s and related diseases, which are collectively known as synucleinopathies. Growing evidence has supported that the same protein can induce remarkably distinct pathological progresses and disease phenotyp...

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Detalles Bibliográficos
Autores principales: Liu, Di, Guo, Jian-Jun, Su, Ji-Hui, Svanbergsson, Alexander, Yuan, Lin, Haikal, Caroline, Li, Wen, Gouras, Gunnar, Li, Jia-Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8215826/
https://www.ncbi.nlm.nih.gov/pubmed/34148543
http://dx.doi.org/10.1186/s40035-021-00242-5