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Serp-1 Promotes Corneal Wound Healing by Facilitating Re-epithelialization and Inhibiting Fibrosis and Angiogenesis

Purpose: Chemical corneal injuries carry a high morbidity and commonly lead to visual impairment. Here, we investigate the role of Serp-1, a serine protease inhibitor, in corneal wound healing. Methods: An alkaline-induced corneal injury was induced in 14 mice. Following injury, five mice received d...

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Detalles Bibliográficos
Autores principales: Ju, Brent, Guo, Owen, Benissan-Messan, Dathe Z., Shawver, McKinley H., Chen, Peng, Geng, Bingchuan, Wei, Siqi, Yaron, Jordan R., Lucas, Alexandra R., Zhu, Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8216079/
https://www.ncbi.nlm.nih.gov/pubmed/34164439
http://dx.doi.org/10.3389/fcvm.2021.649124