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Determination of in vitro human whole blood-to-plasma ratio of THJ-018 utilizing gas chromatography–Mass spectrometry

OBJECTIVES: This study was aimed to determine in vitro human whole blood-to-plasma ratio (K(WB)/(P)) of THJ-018 by gas chromatography/mass spectrometry (GC/MS). MATERIALS AND METHODS: The samples (human blood) were sprayed with THJ-018 and an internal standard and extracted using solid-phase extract...

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Detalles Bibliográficos
Autores principales: Kumar, Sachil, Alkhibery, Remal Nahar Khleel, Bakdash, Abdulsallam, Abdelhady, Mohamed Sultan Mohamed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8216121/
https://www.ncbi.nlm.nih.gov/pubmed/33975994
http://dx.doi.org/10.4103/ijp.IJP_668_19