Modulation of Liver P-Glycoprotien Expression May Contribute to Gossypin Protection against Methotrexate-Induced Hepatotoxicity

OBJECTIVES: Methotrexate (MTX) is a broadly used anticancer. Its major side effect is hepatotoxicity. Gossypin is a flavonoid has a hepatoprotective effect as well as antitumor property. The study aimed at inspecting the protective effect of gossypin against MTX hepatotoxicity. MATERIALS AND METHODS...

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Detalles Bibliográficos
Autores principales: Mohamed, Mervat, El Sheikh, Azza Kamal, Mohammed, Hanaa Hassanien
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8216128/
https://www.ncbi.nlm.nih.gov/pubmed/33975996
http://dx.doi.org/10.4103/ijp.IJP_824_19

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8216128/
https://www.ncbi.nlm.nih.gov/pubmed/33975996
http://dx.doi.org/10.4103/ijp.IJP_824_19

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