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Effect of vorinostat on INK4 family and HDACs 1, 2, and 3 in pancreatic cancer and hepatocellular carcinoma

BACKGROUND AND PURPOSE: In mammalian cells, several distinct surveillance systems, named cell cycle checkpoints, can interrupt normal cell-cycle progression. The cyclin-dependent kinases are negatively regulated by proteins of cyclin-dependent kinases inhibitors comprising INK4 and Cip/Kip families....

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Detalles Bibliográficos
Autores principales: Sanaei, Masumeh, Kavoosi, Fraidoon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8216159/
https://www.ncbi.nlm.nih.gov/pubmed/34221059
http://dx.doi.org/10.4103/1735-5362.314824