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Synergistic regulation of Rgs4 mRNA by HuR and miR-26/RISC in neurons

The negative regulator of G-protein signalling 4 (Rgs4) is linked to several neurologic diseases, e.g. schizophrenia, addiction, seizure and pain perception. Consequently, Rgs4 expression is tightly regulated, resulting in high mRNA and protein turnover. The post-transcriptional control of gene expr...

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Detalles Bibliográficos
Autores principales: Ehses, Janina, Fernández-Moya, Sandra M., Schröger, Luise, Kiebler, Michael A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8216180/
https://www.ncbi.nlm.nih.gov/pubmed/32779957
http://dx.doi.org/10.1080/15476286.2020.1795409