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Novel lactotransferrin-derived synthetic peptides suppress cariogenic bacteria in vitro and arrest dental caries in vivo: [Novel lactotransferrin-derived anticaries peptides]

Objectives: The aim of the study was to design and synthesise novel lactotransferrin-derived antimicrobial peptides (AMPs) with enhanced antibacterial activity against cariogenic bacteria. Methods: We obtained the LF-1 (WKLLRKAWKLLRKA) and LF-2 (GKLIWKLLRKAWKLLRKA) AMPs, based on the N-terminal func...

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Detalles Bibliográficos
Autores principales: Luo, Junyuan, Feng, Zening, Jiang, Wentao, Jiang, Xuelian, Chen, Yue, Lv, Xiaohui, Zhang, Linglin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8216265/
https://www.ncbi.nlm.nih.gov/pubmed/34234894
http://dx.doi.org/10.1080/20002297.2021.1943999