Cargando…

Novel lactotransferrin-derived synthetic peptides suppress cariogenic bacteria in vitro and arrest dental caries in vivo: [Novel lactotransferrin-derived anticaries peptides]

Objectives: The aim of the study was to design and synthesise novel lactotransferrin-derived antimicrobial peptides (AMPs) with enhanced antibacterial activity against cariogenic bacteria. Methods: We obtained the LF-1 (WKLLRKAWKLLRKA) and LF-2 (GKLIWKLLRKAWKLLRKA) AMPs, based on the N-terminal func...

Descripción completa

Detalles Bibliográficos
Autores principales:	Luo, Junyuan, Feng, Zening, Jiang, Wentao, Jiang, Xuelian, Chen, Yue, Lv, Xiaohui, Zhang, Linglin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Taylor & Francis 2021
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8216265/ https://www.ncbi.nlm.nih.gov/pubmed/34234894 http://dx.doi.org/10.1080/20002297.2021.1943999

Ejemplares similares

Novel Lactotransferrin-Derived Antimicrobial Peptide LF-1 Inhibits the Cariogenic Virulence Factors of Streptococcus mutans
por: Luo, Junyuan, et al.
Publicado: (2023)

Analysis of Polymorphisms in the Lactotransferrin Gene Promoter and Dental Caries
por: Brancher, João Armando, et al.
Publicado: (2011)

Analysis of the association between lactotransferrin (LTF) gene polymorphism and dental caries
por: AZEVEDO, Luiza Foltran, et al.
Publicado: (2010)

The association between genetic variants in lactotransferrin and dental caries: a meta- and gene-based analysis
por: Li, Xueyan, et al.
Publicado: (2020)

Design and characterization of Lactotransferrin peptide-loaded dextran-docosahexaenoic acid nanoparticles: an immune modulator for hepatic damage
por: Madkhali, Osama A., et al.
Publicado: (2023)

Lactotransferrin in Asian Elephant (Elephas maximus) Seminal Plasma Correlates with Semen Quality
por: Kiso, Wendy K., et al.
Publicado: (2013)

Lactotransferrin Downregulation Drives the Metastatic Progression in Clear Cell Renal Cell Carcinoma
por: Chiu, I-Jen, et al.
Publicado: (2020)

Lactotransferrin expression is downregulated and affects the mitogen-activated protein kinase pathway in gastric cancer
por: Luo, Gengqiu, et al.
Publicado: (2021)

Lactotransferrin promotes intervertebral disc degeneration by regulating Fas and inhibiting human nucleus pulposus cell apoptosis
por: Zhang, Xiao-Bo, et al.
Publicado: (2022)

Antimicrobial peptide GH12 suppresses cariogenic virulence factors of Streptococcus mutans
por: Wang, Yufei, et al.
Publicado: (2018)

Lactotransferrin gene functional polymorphisms do not influence susceptibility to human immunodeficiency virus-1 mother-to-child transmission in different ethnic groups
por: Zupin, Luisa, et al.
Publicado: (2015)

Lactotransferrin Downregulation Serves as a Potential Predictor for the Therapeutic Effectiveness of mTOR Inhibitors in the Metastatic Clear Cell Renal Cell Carcinoma without PTEN Mutation
por: Zheng, Jing-Quan, et al.
Publicado: (2021)

Targeting cariogenic pathogens and promoting competitiveness of commensal bacteria with a novel pH-responsive antimicrobial peptide
por: Jiang, Wentao, et al.
Publicado: (2022)

Remineralization of enamel caries by an amelogenin-derived peptide and fluoride in vitro
por: Ding, Longjiang, et al.
Publicado: (2020)

Investigation of drug resistance of caries-related streptococci to antimicrobial peptide GH12
por: Li, Xinwei, et al.
Publicado: (2022)

The Unexplored Anticaries Potential of Shiitake Mushroom
por: Avinash, J., et al.
Publicado: (2016)

Anticaries potential of a fluoride foam
por: Benedito, Larissa Caroliny de Brito, et al.
Publicado: (2023)

A statherin-derived peptide promotes hydroxyapatite crystallization and in situ remineralization of artificial enamel caries
por: Wang, Kun, et al.
Publicado: (2018)

Evaluation of a Novel Synthetic Peptide Derived from Cytolytic Mycotoxin Candidalysin
por: Cardoso, Pedro Henrique de Oliveira, et al.
Publicado: (2022)

Anti-biofilm and remineralization effects of chitosan hydrogel containing amelogenin-derived peptide on initial caries lesions
por: Ren, Qian, et al.
Publicado: (2018)

A Nanoparticle-Based Anticaries Vaccine Enhances the Persistent Immune Response To Inhibit Streptococcus mutans and Prevent Caries
por: Yu, You-Bo, et al.
Publicado: (2023)

Comparison of Composition and Anticaries Effect of Galla Chinensis Extracts with Different Isolation Methods
por: Huang, Xuelian, et al.
Publicado: (2017)

Triggering of cancer cell cycle arrest by a novel scorpion venom‐derived peptide—Gonearrestide
por: Li, Bin, et al.
Publicado: (2018)

The Anti-Caries Effects of a Novel Peptide on Dentine Caries: An In Vitro Study
por: Zhang, Olivia Lili, et al.
Publicado: (2023)

Antimicrobial Activity of Novel Synthetic Peptides Derived from Indolicidin and Ranalexin against Streptococcus pneumoniae
por: Jindal, Hassan Mahmood, et al.
Publicado: (2015)

Octominin: A Novel Synthetic Anticandidal Peptide Derived from Defense Protein of Octopus minor
por: Nikapitiya, Chamilani, et al.
Publicado: (2020)

Impact of an Anticaries Mouthrinse on In Vitro Remineralization and Microbial Control
por: Sun, Frank C., et al.
Publicado: (2014)

Anticaries effect of dentifrices with calcium citrate and sodium trimetaphosphate
por: DELBEM, Alberto Carlos Botazzo, et al.
Publicado: (2012)

Frequency of sucrose exposure on the cariogenicity of a biofilm-caries model
por: Díaz-Garrido, Natalia, et al.
Publicado: (2016)

Adjunctive dental therapies in caries-active children: Shifting the cariogenic salivary microbiome from dysbiosis towards non-cariogenic health
por: Lyashenko, Claudia, et al.
Publicado: (2020)

Evaluation of Plant and Fungal Extracts for Their Potential Antigingivitis and Anticaries Activity
por: Spratt, D. A., et al.
Publicado: (2012)

Caries arresting effect of silver diamine fluoride on dentine carious lesion with S. mutans and L. acidophilus dual-species cariogenic biofilm
por: Mei, May L., et al.
Publicado: (2013)

Potentials of Mouthwashes in Disinfecting Cariogenic Bacteria and Biofilms Leading to Inhibition of Caries
por: Oyanagi, Takehiro, et al.
Publicado: (2012)

Effect of emodin on the cariogenic properties of Streptococcus mutans and the development of caries in rats
por: XU, JING-SHU, et al.
Publicado: (2014)

Cariogenicity induced by commercial carbonated beverages in an experimental biofilm-caries model
por: Giacaman, Rodrigo A., et al.
Publicado: (2018)

Bioresponsive nanotherapy for preventing dental caries by inhibiting multispecies cariogenic biofilms
por: Liu, Danfeng, et al.
Publicado: (2021)

Saliva Decreases Sucrose-Induced Cariogenicity in an Experimental Biological Caries Model
por: Giacaman, Rodrigo A., et al.
Publicado: (2023)

Engineered Salivary Peptides Reduce Enamel Demineralization Provoked by Cariogenic S. mutans Biofilm
por: Marin, Lina Maria, et al.
Publicado: (2022)

Chemokine-Derived Peptides: Novel Antimicrobial and Antineoplasic Agents
por: Valdivia-Silva, Julio, et al.
Publicado: (2015)

Synthesis of Novel Carborane-Containing Derivatives of RGD Peptide
por: Vakhrushev, Alexander V., et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_f78nsj7koi1hnqqq5c1nb57sjh