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The multi-functionality of UHRF1: epigenome maintenance and preservation of genome integrity

During S phase, the cooperation between the macromolecular complexes regulating DNA synthesis, epigenetic information maintenance and DNA repair is advantageous for cells, as they can rapidly detect DNA damage and initiate the DNA damage response (DDR). UHRF1 is a fundamental epigenetic regulator; i...

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Detalles Bibliográficos
Autores principales: Mancini, Monica, Magnani, Elena, Macchi, Filippo, Bonapace, Ian Marc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8216287/
https://www.ncbi.nlm.nih.gov/pubmed/33939809
http://dx.doi.org/10.1093/nar/gkab293