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Intra-articular delivery of flurbiprofen sustained release thermogel: improved therapeutic outcome of collagenase II-induced rat knee osteoarthritis

Knee osteoarthritis (OA) is a common degenerative disease. Intra-articular administration of flurbiprofen is frequently employed in clinic to treat OA, while repeated injections are required because of the limited effective duration. To improve therapeutic outcome and prolong the treatment interval,...

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Detalles Bibliográficos
Autores principales: Li, Peinan, Li, Haokun, Shu, Xiaohong, Wu, Moli, Liu, Jia, Hao, Tangna, Cui, Hongxia, Zheng, Lianjie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8216450/
https://www.ncbi.nlm.nih.gov/pubmed/32627602
http://dx.doi.org/10.1080/10717544.2020.1787555