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Altering transcription factor binding reveals comprehensive transcriptional kinetics of a basic gene

Transcription is a vital process activated by transcription factor (TF) binding. The active gene releases a burst of transcripts before turning inactive again. While the basic course of transcription is well understood, it is unclear how binding of a TF affects the frequency, duration and size of a...

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Detalles Bibliográficos
Autores principales: Popp, Achim P, Hettich, Johannes, Gebhardt, J Christof M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8216454/
https://www.ncbi.nlm.nih.gov/pubmed/34060631
http://dx.doi.org/10.1093/nar/gkab443