CD44 alternative splicing senses intragenic DNA methylation in tumors via direct and indirect mechanisms

DNA methylation (meDNA) is a modulator of alternative splicing, and splicing perturbations are involved in tumorigenesis nearly as frequently as DNA mutations. However, the impact of meDNA on tumorigenesis via splicing-mediated mechanisms has not been thoroughly explored. Here, we found that HCT116...

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Detalles Bibliográficos
Autores principales: Batsché, Eric, Yi, Jia, Mauger, Oriane, Kornobis, Etienne, Hopkins, Benjamin, Hanmer-Lloyd, Charlotte, Muchardt, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Gene regulation, Chromatin and Epigenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8216461/
https://www.ncbi.nlm.nih.gov/pubmed/34086943
http://dx.doi.org/10.1093/nar/gkab437

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8216461/
https://www.ncbi.nlm.nih.gov/pubmed/34086943
http://dx.doi.org/10.1093/nar/gkab437

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