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CD44 alternative splicing senses intragenic DNA methylation in tumors via direct and indirect mechanisms
DNA methylation (meDNA) is a modulator of alternative splicing, and splicing perturbations are involved in tumorigenesis nearly as frequently as DNA mutations. However, the impact of meDNA on tumorigenesis via splicing-mediated mechanisms has not been thoroughly explored. Here, we found that HCT116...
Autores principales: | Batsché, Eric, Yi, Jia, Mauger, Oriane, Kornobis, Etienne, Hopkins, Benjamin, Hanmer-Lloyd, Charlotte, Muchardt, Christian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8216461/ https://www.ncbi.nlm.nih.gov/pubmed/34086943 http://dx.doi.org/10.1093/nar/gkab437 |
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