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The conserved sex regulator DMRT1 recruits SOX9 in sexual cell fate reprogramming

Mammalian sexual development commences when fetal bipotential progenitor cells adopt male Sertoli (in XY) or female granulosa (in XX) gonadal cell fates. Differentiation of these cells involves extensive divergence in chromatin state and gene expression, reflecting distinct roles in sexual different...

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Detalles Bibliográficos
Autores principales: Lindeman, Robin E, Murphy, Mark W, Agrimson, Kellie S, Gewiss, Rachel L, Bardwell, Vivian J, Gearhart, Micah D, Zarkower, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8216462/
https://www.ncbi.nlm.nih.gov/pubmed/34096593
http://dx.doi.org/10.1093/nar/gkab448