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The conserved sex regulator DMRT1 recruits SOX9 in sexual cell fate reprogramming
Mammalian sexual development commences when fetal bipotential progenitor cells adopt male Sertoli (in XY) or female granulosa (in XX) gonadal cell fates. Differentiation of these cells involves extensive divergence in chromatin state and gene expression, reflecting distinct roles in sexual different...
Autores principales: | Lindeman, Robin E, Murphy, Mark W, Agrimson, Kellie S, Gewiss, Rachel L, Bardwell, Vivian J, Gearhart, Micah D, Zarkower, David |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8216462/ https://www.ncbi.nlm.nih.gov/pubmed/34096593 http://dx.doi.org/10.1093/nar/gkab448 |
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