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Comparative palatability of orally disintegrating tablets (ODTs) of Praziquantel (L-PZQ and Rac-PZQ) versus current PZQ tablet in African children: A randomized, single-blind, crossover study

BACKGROUND: Praziquantel (PZQ) is currently the only recommended drug for infection and disease caused by the schistosome species that infects humans; however, the current tablet formulation is not suitable for pre-school age children mainly due to its bitterness and the large tablet size. We assess...

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Detalles Bibliográficos
Autores principales: Mahende, Muhidin K., Huber, Eric, Kourany-Lefoll, Elly, Ali, Ali, Hayward, Brooke, Bezuidenhout, Deon, Bagchus, Wilhelmina, Kabanywanyi, Abdunoor M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8216518/
https://www.ncbi.nlm.nih.gov/pubmed/34106922
http://dx.doi.org/10.1371/journal.pntd.0007370