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Epigenetic Plasticity Enables CNS-Trafficking of EBV-infected B Lymphocytes

Subpopulations of B-lymphocytes traffic to different sites and organs to provide diverse and tissue-specific functions. Here, we provide evidence that epigenetic differences confer a neuroinvasive phenotype. An EBV+ B cell lymphoma cell line (M14) with low frequency trafficking to the CNS was neuroa...

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Detalles Bibliográficos
Autores principales: Soldan, Samantha S., Su, Chenhe, Lamontagne, R. Jason, Grams, Nicholas, Lu, Fang, Zhang, Yue, Gesualdi, James D., Frase, Drew M., Tolvinski, Lois E., Martin, Kayla, Messick, Troy E., Fingerut, Jonathan T., Koltsova, Ekaterina, Kossenkov, Andrew, Lieberman, Paul M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8216538/
https://www.ncbi.nlm.nih.gov/pubmed/34106998
http://dx.doi.org/10.1371/journal.ppat.1009618