Single cell analysis of host response to helminth infection reveals the clonal breadth, heterogeneity, and tissue-specific programming of the responding CD4(+) T cell repertoire

The CD4(+) T cell response is critical to host protection against helminth infection. How this response varies across different hosts and tissues remains an important gap in our understanding. Using IL-4-reporter mice to identify responding CD4(+) T cells to Nippostrongylus brasiliensis infection, T...

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Detalles Bibliográficos
Autores principales: Brown, Ivy K., Dyjack, Nathan, Miller, Mindy M., Krovi, Harsha, Rios, Cydney, Woolaver, Rachel, Harmacek, Laura, Tu, Ting-Hui, O’Connor, Brian P., Danhorn, Thomas, Vestal, Brian, Gapin, Laurent, Pinilla, Clemencia, Seibold, Max A., Scott-Browne, James, Santos, Radleigh G., Reinhardt, R. Lee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8216541/
https://www.ncbi.nlm.nih.gov/pubmed/34106992
http://dx.doi.org/10.1371/journal.ppat.1009602

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8216541/
https://www.ncbi.nlm.nih.gov/pubmed/34106992
http://dx.doi.org/10.1371/journal.ppat.1009602

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