The leucine-NH4(+) uptake regulator Any1 limits growth as part of a general amino acid control response to loss of La protein by fission yeast

The sla1(+) gene of Schizosachharoymces pombe encodes La protein which promotes proper processing of precursor-tRNAs. Deletion of sla1 (sla1Δ) leads to disrupted tRNA processing and sensitivity to target of rapamycin (TOR) inhibition. Consistent with this, media containing NH4(+) inhibits leucine up...

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Detalles Bibliográficos
Autores principales: Cherkasova, Vera, Iben, James R., Pridham, Kevin J., Kessler, Alan C., Maraia, Richard J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8216550/
https://www.ncbi.nlm.nih.gov/pubmed/34153074
http://dx.doi.org/10.1371/journal.pone.0253494

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8216550/
https://www.ncbi.nlm.nih.gov/pubmed/34153074
http://dx.doi.org/10.1371/journal.pone.0253494

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