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Structural and genetic convergence of HIV-1 neutralizing antibodies in vaccinated non-human primates

A primary goal of HIV-1 vaccine development is the consistent elicitation of protective, neutralizing antibodies. While highly similar neutralizing antibodies (nAbs) have been isolated from multiple HIV-infected individuals, it is unclear whether vaccination can consistently elicit highly similar nA...

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Detalles Bibliográficos
Autores principales: Cai, Fangping, Chen, Wei-Hung, Wu, Weimin, Jones, Julia A., Choe, Misook, Gohain, Neelakshi, Shen, Xiaoying, LaBranche, Celia, Eaton, Amanda, Sutherland, Laura, Lee, Esther M., Hernandez, Giovanna E., Wu, Nelson R., Scearce, Richard, Seaman, Michael S., Moody, M. Anthony, Santra, Sampa, Wiehe, Kevin, Tomaras, Georgia D., Wagh, Kshitij, Korber, Bette, Bonsignori, Mattia, Montefiori, David C., Haynes, Barton F., de Val, Natalia, Joyce, M. Gordon, Saunders, Kevin O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8216552/
https://www.ncbi.nlm.nih.gov/pubmed/34086838
http://dx.doi.org/10.1371/journal.ppat.1009624