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Impaired DNA Repair Fidelity in a Breast Cancer Patient With Adverse Reactions to Radiotherapy

We tested the hypothesis that differences in DNA double-strand break (DSB) repair fidelity underlies differences in individual radiosensitivity and, consequently, normal tissue reactions to radiotherapy. Fibroblast cultures derived from a radio-sensitive (RS) breast cancer patient with grade 3 adver...

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Detalles Bibliográficos
Autores principales: Alsbeih, Ghazi, Al-Harbi, Najla, Ismail, Sheikh, Story, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8216558/
https://www.ncbi.nlm.nih.gov/pubmed/34164366
http://dx.doi.org/10.3389/fpubh.2021.647563