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Single-cell transcriptomics defines heterogeneity of epicardial cells and fibroblasts within the infarcted murine heart

In the adult heart, the epicardium becomes activated after injury, contributing to cardiac healing by secretion of paracrine factors. Here, we analyzed by single-cell RNA sequencing combined with RNA in situ hybridization and lineage tracing of Wilms tumor protein 1-positive (WT1(+)) cells, the cell...

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Detalles Bibliográficos
Autores principales: Hesse, Julia, Owenier, Christoph, Lautwein, Tobias, Zalfen, Ria, Weber, Jonas F, Ding, Zhaoping, Alter, Christina, Lang, Alexander, Grandoch, Maria, Gerdes, Norbert, Fischer, Jens W, Klau, Gunnar W, Dieterich, Christoph, Köhrer, Karl, Schrader, Jürgen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8216715/
https://www.ncbi.nlm.nih.gov/pubmed/34152268
http://dx.doi.org/10.7554/eLife.65921