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SIRT1 regulates sphingolipid metabolism and neural differentiation of mouse embryonic stem cells through c-Myc-SMPDL3B

Sphingolipids are important structural components of cell membranes and prominent signaling molecules controlling cell growth, differentiation, and apoptosis. Sphingolipids are particularly abundant in the brain, and defects in sphingolipid degradation are associated with several human neurodegenera...

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Detalles Bibliográficos
Autores principales: Fan, Wei, Tang, Shuang, Fan, Xiaojuan, Fang, Yi, Xu, Xiaojiang, Li, Leping, Xu, Jian, Li, Jian-Liang, Wang, Zefeng, Li, Xiaoling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8216717/
https://www.ncbi.nlm.nih.gov/pubmed/34042046
http://dx.doi.org/10.7554/eLife.67452