Cargando…

SIRT1 regulates sphingolipid metabolism and neural differentiation of mouse embryonic stem cells through c-Myc-SMPDL3B

Sphingolipids are important structural components of cell membranes and prominent signaling molecules controlling cell growth, differentiation, and apoptosis. Sphingolipids are particularly abundant in the brain, and defects in sphingolipid degradation are associated with several human neurodegenera...

Descripción completa

Detalles Bibliográficos
Autores principales:	Fan, Wei, Tang, Shuang, Fan, Xiaojuan, Fang, Yi, Xu, Xiaojiang, Li, Leping, Xu, Jian, Li, Jian-Liang, Wang, Zefeng, Li, Xiaoling
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	eLife Sciences Publications, Ltd 2021
Materias:	Cell Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8216717/ https://www.ncbi.nlm.nih.gov/pubmed/34042046 http://dx.doi.org/10.7554/eLife.67452

Ejemplares similares

The SIRT1-c-Myc axis in regulation of stem cells
por: Fan, Wei, et al.
Publicado: (2023)

SIRT1 Limits Adipocyte Hyperplasia through c-Myc Inhibition
por: Abdesselem, Houari, et al.
Publicado: (2016)

The Lipid-Modifying Enzyme SMPDL3B Negatively Regulates Innate Immunity
por: Heinz, Leonhard X., et al.
Publicado: (2015)

SMPDL3b modulates insulin receptor signaling in diabetic kidney disease
por: Mitrofanova, A., et al.
Publicado: (2019)

SIRT1 regulates cardiomyocyte alignment during maturation
por: Fang, Yi, et al.
Publicado: (2022)

SMPDL3B Predicts Poor Prognosis and Contributes to Development of Acute Myeloid Leukemia
por: Qu, Huiqing, et al.
Publicado: (2021)

The Role of Sphingolipid Metabolism in Bone Remodeling
por: Qi, Tang, et al.
Publicado: (2021)

Phosphodiesterase SMPDL3B Gene Expression as Independent Outcome Prediction Marker in Localized Prostate Cancer
por: Waldbillig, Frank, et al.
Publicado: (2020)

Crosstalk Between SMPDL3b and NADPH Oxidases Mediates Radiation-Induced Damage of Renal Podocytes
por: Azzam, Patrick, et al.
Publicado: (2021)

tRNA synthetase counteracts c-Myc to develop functional vasculature
por: Shi, Yi, et al.
Publicado: (2014)

The GARP complex is required for cellular sphingolipid homeostasis
por: Fröhlich, Florian, et al.
Publicado: (2015)

Editorial: Sphingolipids in Infection Control
por: Seibel, Jürgen, et al.
Publicado: (2021)

EGFR deficiency leads to impaired self-renewal and pluripotency of mouse embryonic stem cells
por: Yu, Miaoying, et al.
Publicado: (2019)

Porcine reproductive and respiratory syndrome virus upregulates SMPDL3B to promote viral replication by modulating lipid metabolism
por: Shen, Huan-Huan, et al.
Publicado: (2023)

BRD7 Promotes Cell Proliferation and Tumor Growth Through Stabilization of c-Myc in Colorectal Cancer
por: Zhao, Ran, et al.
Publicado: (2021)

Sulfation of Glycosaminoglycans Modulates the Cell Cycle of Embryonic Mouse Spinal Cord Neural Stem Cells
por: Schaberg, Elena, et al.
Publicado: (2021)

Lessons in aging from Myc knockout mouse models
por: Prochownik, Edward V., et al.
Publicado: (2023)

MYC Enhances Cholesterol Biosynthesis and Supports Cell Proliferation Through SQLE
por: Yang, Fan, et al.
Publicado: (2021)

Functions of Sphingolipids in Pathogenesis During Host–Pathogen Interactions
por: Wang, Jian, et al.
Publicado: (2021)

Sphingolipid Organization in the Plasma Membrane and the Mechanisms That Influence It
por: Kraft, Mary L.
Publicado: (2017)

Diverse Facets of Sphingolipid Involvement in Bacterial Infections
por: Kunz, Tobias C., et al.
Publicado: (2019)

Corrigendum: MYC Enhances Cholesterol Biosynthesis and Supports Cell Proliferation Through SQLE
por: Yang, Fan, et al.
Publicado: (2021)

Wild-Type p53-Induced Phosphatase 1 Plays a Positive Role in Hematopoiesis in the Mouse Embryonic Head
por: He, Wenyan, et al.
Publicado: (2021)

Generation of Multipotential NG2 Progenitors From Mouse Embryonic Stem Cell-Derived Neural Stem Cells
por: Otsu, Masahiro, et al.
Publicado: (2021)

Embryonic Hypotaurine Levels Contribute to Strain-Dependent Susceptibility in Mouse Models of Valproate-Induced Neural Tube Defects
por: Steele, John W., et al.
Publicado: (2022)

Sphingolipids as Modulators of SARS-CoV-2 Infection
por: Törnquist, Kid, et al.
Publicado: (2021)

Ethylene Modulates Sphingolipid Synthesis in Arabidopsis
por: Wu, Jian-xin, et al.
Publicado: (2015)

A c-Myc–SIRT1 feedback loop regulates cell growth and transformation
por: Yuan, Jian, et al.
Publicado: (2009)

A sphingolipid-dependent diffusion barrier confines ER stress to the yeast mother cell
por: Clay, Lori, et al.
Publicado: (2014)

A Comprehensive Review on the Manipulation of the Sphingolipid Pathway by Pathogenic Bacteria
por: Rolando, Monica, et al.
Publicado: (2019)

Lipid Rafts, Sphingolipids, and Ergosterol in Yeast Vacuole Fusion and Maturation
por: Hurst, Logan R., et al.
Publicado: (2020)

Sphingolipid Metabolism and Transport in Chlamydia trachomatis and Chlamydia psittaci Infections
por: Banhart, Sebastian, et al.
Publicado: (2019)

LHPP-Mediated Histidine Dephosphorylation Suppresses the Self-Renewal of Mouse Embryonic Stem Cells
por: Xia, Rong Mu, et al.
Publicado: (2021)

Mechanism of Axonal Contractility in Embryonic Drosophila Motor Neurons In Vivo
por: Tofangchi, Alireza, et al.
Publicado: (2016)

Sphingolipids at Plasmodesmata: Structural Components and Functional Modulators
por: Zhang, Yingying, et al.
Publicado: (2022)

Autophagy in the light of sphingolipid metabolism
por: Harvald, Eva Bang, et al.
Publicado: (2015)

mTORC1-Rps15 Axis Contributes to the Mechanisms Underlying Global Translation Reduction During Senescence of Mouse Embryonic Fibroblasts
por: Wu, Su, et al.
Publicado: (2019)

The Role of Mcl-1 in Embryonic Neural Precursor Cell Apoptosis
por: Flemmer, Robert T., et al.
Publicado: (2021)

Preparation of Mouse Embryonic Fibroblast Cells Suitable for Culturing Human Embryonic and Induced Pluripotent Stem Cells
por: Jozefczuk, Justyna, et al.
Publicado: (2012)

Corrigendum: A Comprehensive Review on the Manipulation of the Sphingolipid Pathway by Pathogenic Bacteria
por: Rolando, Monica, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_ek6g6hd863ccaoule2as1dritl