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Mangiferin Alleviates Mitochondrial ROS in Nucleus Pulposus Cells and Protects against Intervertebral Disc Degeneration via Suppression of NF-κB Signaling Pathway

Intervertebral disc degeneration (IVDD), one of the most common clinical diseases worldwide, causes disc herniation and sciatica. Recent studies have identified the involvement of mitochondrial dysfunction, inflammatory responses, and extracellular matrix degradation in IVDD. Mangiferin is known to...

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Detalles Bibliográficos
Autores principales: Yu, Haichao, Hou, Guowei, Cao, Jiankang, Yin, Yanyu, Zhao, Yunpeng, Cheng, Lei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8216826/
https://www.ncbi.nlm.nih.gov/pubmed/34234886
http://dx.doi.org/10.1155/2021/6632786