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Mangiferin Alleviates Mitochondrial ROS in Nucleus Pulposus Cells and Protects against Intervertebral Disc Degeneration via Suppression of NF-κB Signaling Pathway
Intervertebral disc degeneration (IVDD), one of the most common clinical diseases worldwide, causes disc herniation and sciatica. Recent studies have identified the involvement of mitochondrial dysfunction, inflammatory responses, and extracellular matrix degradation in IVDD. Mangiferin is known to...
Autores principales: | Yu, Haichao, Hou, Guowei, Cao, Jiankang, Yin, Yanyu, Zhao, Yunpeng, Cheng, Lei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8216826/ https://www.ncbi.nlm.nih.gov/pubmed/34234886 http://dx.doi.org/10.1155/2021/6632786 |
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