Process Optimization for the Continuous Production of a Gastroretentive Dosage Form Based on Melt Foaming
Several drugs have poor oral bioavailability due to low or incomplete absorption which is affected by various effects as pH, motility of GI, and enzyme activity. The gastroretentive drug delivery systems are able to deal with these problems by prolonging the gastric residence time, while increasing...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8217006/ https://www.ncbi.nlm.nih.gov/pubmed/34155595 http://dx.doi.org/10.1208/s12249-021-02066-y |