Spray-Congealing and Wet-Sieving as Alternative Processes for Engineering of Inhalation Carrier Particles: Comparison of Surface Properties, Blending and In Vitro Performance

PURPOSE: Traditionally, α-lactose monohydrate is the carrier of choice in dry powder inhaler (DPI) formulations. Nonetheless, other sugars, such as D-mannitol, have emerged as potential alternatives. Herein, we explored different particle engineering processes to produce D-mannitol carriers for inha...

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Detalles Bibliográficos
Autores principales: Pinto, Joana T., Zellnitz, Sarah, Guidi, Tomaso, Schiaretti, Francesca, Schroettner, Hartmuth, Paudel, Amrit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8217042/
https://www.ncbi.nlm.nih.gov/pubmed/34114162
http://dx.doi.org/10.1007/s11095-021-03061-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8217042/
https://www.ncbi.nlm.nih.gov/pubmed/34114162
http://dx.doi.org/10.1007/s11095-021-03061-5

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