Loss of Ephrin B2 Receptor (EPHB2) Sets Lipid Rheostat by Regulating Proteins DGAT1 and ATGL Inducing Lipid Droplet Storage in Prostate Cancer Cells

Lipid droplet (LD) accumulation in cancer results from aberrant metabolic reprograming due to increased lipid uptake, diminished lipolysis and/or de novo lipid synthesis. Initially implicated in storage and lipid trafficking in adipocytes, LDs are more recently recognized to fuel key functions assoc...

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Detalles Bibliográficos
Autores principales: Morales, Alejandro, Greenberg, Max, Nardi, Francesca, Gil, Victoria, Hayward, Simon W., Crawford, Susan E., Franco, Omar E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8217088/
https://www.ncbi.nlm.nih.gov/pubmed/33824421
http://dx.doi.org/10.1038/s41374-021-00583-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8217088/
https://www.ncbi.nlm.nih.gov/pubmed/33824421
http://dx.doi.org/10.1038/s41374-021-00583-9

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