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Endosome Dysregulation in Down Syndrome: A Potential Contributor to Alzheimer Disease Pathology
Intracellular protein trafficking via the endosomes plays a key role in the maintenance of normal neuronal function. Although many diseases of the central nervous system exhibit specific pathological hallmarks, abnormalities of the endosome system are common traits for several of them, including Alz...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley & Sons, Inc.
2021
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8217102/ https://www.ncbi.nlm.nih.gov/pubmed/33547827 http://dx.doi.org/10.1002/ana.26042 |