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Systematic detection of functional proteoform groups from bottom-up proteomic datasets

To a large extent functional diversity in cells is achieved by the expansion of molecular complexity beyond that of the coding genome. Various processes create multiple distinct but related proteins per coding gene – so-called proteoforms – that expand the functional capacity of a cell. Evaluating p...

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Detalles Bibliográficos
Autores principales: Bludau, Isabell, Frank, Max, Dörig, Christian, Cai, Yujia, Heusel, Moritz, Rosenberger, George, Picotti, Paola, Collins, Ben C., Röst, Hannes, Aebersold, Ruedi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8217233/
https://www.ncbi.nlm.nih.gov/pubmed/34155216
http://dx.doi.org/10.1038/s41467-021-24030-x