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Map2k5-Deficient Mice Manifest Phenotypes and Pathological Changes of Dopamine Deficiency in the Central Nervous System

MAP2K5, a member of the MAPK family, is associated with central nervous system disorders. However, neural functional of Map2k5 from animal models were not well examined so far. Here, we established a Map2k5-targeted knockout mouse model to investigate the behavior phenotypes and its underlying molec...

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Detalles Bibliográficos
Autores principales: Huang, Yumeng, Wang, Pei, Morales, Rodrigo, Luo, Qi, Ma, Jianfang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8217467/
https://www.ncbi.nlm.nih.gov/pubmed/34168549
http://dx.doi.org/10.3389/fnagi.2021.651638