Vinaxanthone inhibits Semaphorin3A induced axonal growth cone collapse in embryonic neurons but fails to block its growth promoting effects on adult neurons

Semaphorin3A is considered a classical repellent molecule for developing neurons and a potent inhibitor of regeneration after nervous system trauma. Vinaxanthone and other Sema3A inhibitors are currently being tested as possible therapeutics to promote nervous system regeneration from injury. Our pr...

Descripción completa

Detalles Bibliográficos
Autores principales: Ivakhnitskaia, Evguenia, Chin, Matthew R., Siegel, Dionicio, Guaiquil, Victor H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8217491/
https://www.ncbi.nlm.nih.gov/pubmed/34155284
http://dx.doi.org/10.1038/s41598-021-92375-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8217491/
https://www.ncbi.nlm.nih.gov/pubmed/34155284
http://dx.doi.org/10.1038/s41598-021-92375-w

Ejemplares similares