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Vinaxanthone inhibits Semaphorin3A induced axonal growth cone collapse in embryonic neurons but fails to block its growth promoting effects on adult neurons
Semaphorin3A is considered a classical repellent molecule for developing neurons and a potent inhibitor of regeneration after nervous system trauma. Vinaxanthone and other Sema3A inhibitors are currently being tested as possible therapeutics to promote nervous system regeneration from injury. Our pr...
Autores principales: | Ivakhnitskaia, Evguenia, Chin, Matthew R., Siegel, Dionicio, Guaiquil, Victor H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8217491/ https://www.ncbi.nlm.nih.gov/pubmed/34155284 http://dx.doi.org/10.1038/s41598-021-92375-w |
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