Tuning SAS-6 architecture with monobodies impairs distinct steps of centriole assembly

Centrioles are evolutionarily conserved multi-protein organelles essential for forming cilia and centrosomes. Centriole biogenesis begins with self-assembly of SAS-6 proteins into 9-fold symmetrical ring polymers, which then stack into a cartwheel that scaffolds organelle formation. The importance o...

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Detalles Bibliográficos
Autores principales: Hatzopoulos, Georgios N., Kükenshöner, Tim, Banterle, Niccolò, Favez, Tatiana, Flückiger, Isabelle, Hamel, Virginie, Andany, Santiago, Fantner, Georg E., Hantschel, Oliver, Gönczy, Pierre
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8217511/
https://www.ncbi.nlm.nih.gov/pubmed/34155202
http://dx.doi.org/10.1038/s41467-021-23897-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8217511/
https://www.ncbi.nlm.nih.gov/pubmed/34155202
http://dx.doi.org/10.1038/s41467-021-23897-0

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