A genome-wide CRISPR/Cas9 screen to identify phagocytosis modulators in monocytic THP-1 cells

Phagocytosis of microbial pathogens, dying or dead cells, and cell debris is essential to maintain tissue homeostasis. Impairment of these processes is associated with autoimmunity, developmental defects and toxic protein accumulation. However, the underlying molecular mechanisms of phagocytosis rem...

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Detalles Bibliográficos
Autores principales: Lindner, Benjamin, Martin, Eva, Steininger, Monika, Bundalo, Aleksandra, Lenter, Martin, Zuber, Johannes, Schuler, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8217514/
https://www.ncbi.nlm.nih.gov/pubmed/34155263
http://dx.doi.org/10.1038/s41598-021-92332-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8217514/
https://www.ncbi.nlm.nih.gov/pubmed/34155263
http://dx.doi.org/10.1038/s41598-021-92332-7

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