The RNA-binding protein LUC7L2 mediates MITA/STING intron retention to negatively regulate innate antiviral response

MITA (also known as STING) is an ER-located adaptor protein, which mediates DNA-triggered innate immune response and is critically involved in autoimmune diseases and tumorigenesis. MITA is regulated by post-translational modifications, but how post-transcriptional mechanisms are involved in the reg...

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Detalles Bibliográficos
Autores principales: Li, Chen, Feng, Lu, Luo, Wei-Wei, Lei, Cao-Qi, Li, Mi, Shu, Hong-Bing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Singapore 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8217528/
https://www.ncbi.nlm.nih.gov/pubmed/34155193
http://dx.doi.org/10.1038/s41421-021-00277-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8217528/
https://www.ncbi.nlm.nih.gov/pubmed/34155193
http://dx.doi.org/10.1038/s41421-021-00277-y

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