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The RNA-binding protein LUC7L2 mediates MITA/STING intron retention to negatively regulate innate antiviral response
MITA (also known as STING) is an ER-located adaptor protein, which mediates DNA-triggered innate immune response and is critically involved in autoimmune diseases and tumorigenesis. MITA is regulated by post-translational modifications, but how post-transcriptional mechanisms are involved in the reg...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Springer Singapore
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8217528/ https://www.ncbi.nlm.nih.gov/pubmed/34155193 http://dx.doi.org/10.1038/s41421-021-00277-y |