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High-resolution transcriptional landscape of xeno-free human induced pluripotent stem cell-derived cerebellar organoids

Current protocols for producing cerebellar neurons from human pluripotent stem cells (hPSCs) often rely on animal co-culture and mostly exist as monolayers, limiting their capability to recapitulate the complex processes in the developing cerebellum. Here, we employed a robust method, without the ne...

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Detalles Bibliográficos
Autores principales: Nayler, Samuel, Agarwal, Devika, Curion, Fabiola, Bowden, Rory, Becker, Esther B. E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8217544/
https://www.ncbi.nlm.nih.gov/pubmed/34155230
http://dx.doi.org/10.1038/s41598-021-91846-4