Impaired stem cell differentiation and somatic cell reprogramming in DIDO3 mutants with altered RNA processing and increased R-loop levels

Embryonic stem cell (ESC) differentiation and somatic cell reprogramming are biological processes governed by antagonistic expression or repression of a largely common set of genes. Accurate regulation of gene expression is thus essential for both processes, and alterations in RNA processing are pre...

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Detalles Bibliográficos
Autores principales: Fütterer, Agnes, Talavera-Gutiérrez, Amaia, Pons, Tirso, de Celis, Jesús, Gutiérrez, Julio, Domínguez Plaza, Verónica, Martínez-A, Carlos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8217545/
https://www.ncbi.nlm.nih.gov/pubmed/34155199
http://dx.doi.org/10.1038/s41419-021-03906-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8217545/
https://www.ncbi.nlm.nih.gov/pubmed/34155199
http://dx.doi.org/10.1038/s41419-021-03906-2

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