Interaction between genetic predisposition, smoking, and dementia risk: a population-based cohort study

We evaluated whether the association between cigarette smoking and dementia risk is modified by genetic predisposition including apolipoprotein E (APOE) genotype and polygenic risk (excluding the APOE region). We included 193,198 UK Biobank participants aged 60–73 years without dementia at baseline....

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Detalles Bibliográficos
Autores principales: Zhang, Na, Ranson, Janice M., Zheng, Zhi-Jie, Hannon, Eilis, Zhou, Zhenwei, Kong, Xuejun, Llewellyn, David J., King, Daniel A., Huang, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8217565/
https://www.ncbi.nlm.nih.gov/pubmed/34155245
http://dx.doi.org/10.1038/s41598-021-92304-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8217565/
https://www.ncbi.nlm.nih.gov/pubmed/34155245
http://dx.doi.org/10.1038/s41598-021-92304-x

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