Exploiting hiPSCs in Leber's Hereditary Optic Neuropathy (LHON): Present Achievements and Future Perspectives

More than 30 years after discovering Leber's hereditary optic neuropathy (LHON) as the first maternally inherited disease associated with homoplasmic mtDNA mutations, we still struggle to achieve effective therapies. LHON is characterized by selective degeneration of retinal ganglion cells (RGC...

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Detalles Bibliográficos
Autores principales: Peron, Camille, Maresca, Alessandra, Cavaliere, Andrea, Iannielli, Angelo, Broccoli, Vania, Carelli, Valerio, Di Meo, Ivano, Tiranti, Valeria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Neurology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8217617/
https://www.ncbi.nlm.nih.gov/pubmed/34168607
http://dx.doi.org/10.3389/fneur.2021.648916

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8217617/
https://www.ncbi.nlm.nih.gov/pubmed/34168607
http://dx.doi.org/10.3389/fneur.2021.648916

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