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Efficient Secretion of Murine IL-2 From an Attenuated Strain of Clostridium sporogenes, a Novel Delivery Vehicle for Cancer Immunotherapy

Despite a history dating back to the 1800s, using Clostridium bacteria to treat cancer has not advanced beyond the observation that they can colonise and partially destroy solid tumours. Progress has been hampered by their inability to eradicate the viable portion of tumours, and an instinctive anxi...

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Detalles Bibliográficos
Autores principales: Kubiak, Aleksandra M., Bailey, Tom S., Dubois, Ludwig J., Theys, Jan, Lambin, Philippe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8217651/
https://www.ncbi.nlm.nih.gov/pubmed/34168629
http://dx.doi.org/10.3389/fmicb.2021.669488