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Secreted inhibitors drive the loss of regeneration competence in Xenopus limbs

Absence of a specialized wound epidermis is hypothesized to block limb regeneration in higher vertebrates. However, the factors preventing its formation in regeneration-incompetent animals are poorly understood. To characterize the endogenous molecular and cellular regulators of specialized wound ep...

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Detalles Bibliográficos
Autores principales: Aztekin, Can, Hiscock, Tom W., Gurdon, John, Jullien, Jerome, Marioni, John, Simons, Benjamin David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8217717/
https://www.ncbi.nlm.nih.gov/pubmed/34105722
http://dx.doi.org/10.1242/dev.199158