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NEK2 Promotes Cell Proliferation and Glycolysis by Regulating PKM2 Abundance via Phosphorylation in Diffuse Large B-Cell Lymphoma

Diffuse large B-cell lymphoma (DLBCL) is the most frequent and commonly diagnosed subtype of NHL, which is characterized by high heterogeneity and malignancy, and most DLBCL patients are at advanced stages. The serine/threonine kinase NEK2 (NIMA-related kinase 2), a member of NIMA-related kinase (NE...

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Detalles Bibliográficos
Autores principales: Zhou, Lingna, Ding, Liya, Gong, Yuqi, Zhao, Jing, Zhang, Jing, Mao, Zhengrong, Wang, Zhe, Zhang, Wei, Zhou, Ren
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8217770/
https://www.ncbi.nlm.nih.gov/pubmed/34168996
http://dx.doi.org/10.3389/fonc.2021.677763