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Endogenous reverse transcriptase and RNase H-mediated antiviral mechanism in embryonic stem cells

Nucleic acid-based systems play important roles in antiviral defense, including CRISPR/Cas that adopts RNA-guided DNA cleavage to prevent DNA phage infection and RNA interference (RNAi) that employs RNA-guided RNA cleavage to defend against RNA virus infection. Here, we report a novel type of nuclei...

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Detalles Bibliográficos
Autores principales: Wu, Junyu, Wu, Chunyan, Xing, Fan, Cao, Liu, Zeng, Weijie, Guo, Liping, Li, Ping, Zhong, Yongheng, Jiang, Hualian, Luo, Manhui, Shi, Guang, Bu, Lang, Ji, Yanxi, Hou, Panpan, Peng, Hong, Huang, Junjiu, Li, Chunmei, Guo, Deyin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Singapore 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8217788/
https://www.ncbi.nlm.nih.gov/pubmed/34158624
http://dx.doi.org/10.1038/s41422-021-00524-7