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Endogenous reverse transcriptase and RNase H-mediated antiviral mechanism in embryonic stem cells
Nucleic acid-based systems play important roles in antiviral defense, including CRISPR/Cas that adopts RNA-guided DNA cleavage to prevent DNA phage infection and RNA interference (RNAi) that employs RNA-guided RNA cleavage to defend against RNA virus infection. Here, we report a novel type of nuclei...
Autores principales: | , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Singapore
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8217788/ https://www.ncbi.nlm.nih.gov/pubmed/34158624 http://dx.doi.org/10.1038/s41422-021-00524-7 |