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Genetic Alterations in Gliomas Remodel the Tumor Immune Microenvironment and Impact Immune-Mediated Therapies

High grade gliomas are malignant brain tumors that arise in the central nervous system, in patients of all ages. Currently, the standard of care, entailing surgery and chemo radiation, exhibits a survival rate of 14-17 months. Thus, there is an urgent need to develop new therapeutic strategies for t...

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Detalles Bibliográficos
Autores principales: Garcia-Fabiani, Maria B., Haase, Santiago, Comba, Andrea, Carney, Stephen, McClellan, Brandon, Banerjee, Kaushik, Alghamri, Mahmoud S., Syed, Faisal, Kadiyala, Padma, Nunez, Felipe J., Candolfi, Marianela, Asad, Antonela, Gonzalez, Nazareno, Aikins, Marisa E., Schwendeman, Anna, Moon, James J., Lowenstein, Pedro R., Castro, Maria G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8217836/
https://www.ncbi.nlm.nih.gov/pubmed/34168976
http://dx.doi.org/10.3389/fonc.2021.631037